Arbesfeld and her team isolated DNA samples from 22 mummies. They then sequenced the genetic material in the hunt for mutations. This was not easy. Arbesfeld says that after many tries, her team found one specific mutation in a gene called APC. This gene is important. The APC gene is known to be involved in the development of cancer. Arbesfeld explains that the APC gene is what she calls the “gatekeeper” for the development of cancer. This information lead Arbesfeld to this hypothesis: If our ancestors with the genetic mutation for colon cancer lived long enough, they would have developed the disease, just like us. Arbesfeld says her next step is to sequence samples from other sources for a larger follow-up study. She says understanding our genetic past can better explain the present. And understanding a disease’s genetic past can help to handle the disease’s future.
Title: Mummies Contain Clues to Colon Cancer
Content: <div id='article-page'><div id='article-content' data-media-url='//news-app-staging.s3.amazonaws.com' data-base-url='//news-app-staging.herokuapp.com' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/colon_audio.m4a' data-capture-url='//staging.analytics.lingraphica.com/events/capture_news' data-article-title='Mummies Contain Clues to Colon Cancer' data-article-id='1366'><script src='//news-app-staging.herokuapp.com/javascripts/getscripts.js'></script><link rel='stylesheet' href='//news-app-staging.herokuapp.com/stylesheets/article.css' type='text/css' /><div class='article'><p><span data-start-time='0' data-end-time='5854'>Arbesfeld and her team isolated DNA samples from 22 mummies. </span> <span data-start-time='5854' data-end-time='11708'>They then sequenced the genetic material in the hunt for mutations. </span> <span data-start-time='11708' data-end-time='14313'>This was not easy. </span> <span data-start-time='14313' data-end-time='24083'>Arbesfeld says that after many tries, her team found one specific mutation in a gene called APC.</span> <span data-start-time='24083' data-end-time='26979'>This gene is important. </span> <span data-start-time='26979' data-end-time='32271'>The APC gene is known to be involved in the development of cancer. </span> <span data-start-time='32271' data-end-time='42771'>Arbesfeld explains that the APC gene is what she calls the “gatekeeper” for the development of cancer.</span> <span data-start-time='42771' data-end-time='59458'>This information lead Arbesfeld to this hypothesis: If our ancestors with the genetic mutation for colon cancer lived long enough, they would have developed the disease, just like us.</span> <span data-start-time='59458' data-end-time='69396'>Arbesfeld says her next step is to sequence samples from other sources for a larger follow-up study. </span> <span data-start-time='69396' data-end-time='75354'>She says understanding our genetic past can better explain the present.</span> <span data-start-time='75354' data-end-time='82875'>And understanding a disease’s genetic past can help to handle the disease’s future.</span> </p></div><div class='control-buttons-sticky' style='display:none;'><div class='control-buttons'><button title='Back' class='back' disabled='disabled'></button><button title='Play' class='play' disabled='disabled'></button><button title='Pause' class='pause' style='display:none;'></button><button title='Forward' class='forward' disabled='disabled'></button><button class='finished-reading' style='display:none;'>Done</button></div></div></div><div id='article-media'><div id='media-image'><img src='https://news-app-production.s3.amazonaws.com/articles/934/mum_img.jpg'/></div></div><div id='question-content' style='display:none;'><div class='vocabulary_question question-container' data-question-id=5674 data-hint-location='42771' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/what_does_hypothesis_mean.m4a'>What does hypothesis mean?</div><div class='choices' data-correct-choice='an idea or theory'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/a_permanent_change.m4a'><span>a permanent change</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/special_chemicals.m4a'><span>special chemicals</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/the_differences_in_living_things.m4a'><span>the differences in living things</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/an_idea_or_theory.m4a'><span>an idea or theory</span></div></div></div><div class='multiple_choice_question question-container' data-question-id=5675 data-hint-location='26979' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/what_is_the_apc_gene_involved_in.m4a'>What is the APC gene involved in?</div><div class='choices' data-correct-choice='development of cancer'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/digestion.m4a'><span>digestion</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/photosynthesis.m4a'><span>photosynthesis</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/development_of_cancer.m4a'><span>development of cancer</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/fertility.m4a'><span>fertility</span></div></div></div><div class='sentence_completion_question question-container' data-question-id=5676 data-hint-location='69396' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/understanding_our__blank__past_can_better_explain_the_present.m4a'>Understanding our <span class='blank'>genetic</span> past can better explain the present.</div><div class='choices' data-correct-choice='genetic'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/genetic.m4a'><span>genetic</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/historic.m4a'><span>historic</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/ancestors.m4a'><span>ancestors</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/934/society.m4a'><span>society</span></div></div></div><div class='question-buttons'><button class='skip-button'></button><button class='hint-button'></button><button 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