Arbesfeld and her team isolated DNA samples from 22 mummies. They then sequenced the genetic material in the hunt for mutations. This was not easy. Arbesfeld says that after many tries, her team found one specific mutation in a gene called APC. This gene is important. The APC gene is known to be involved in the development of cancer. Arbesfeld explains that the APC gene is what she calls the “gatekeeper” for the development of cancer. This information lead Arbesfeld to this hypothesis: If our ancestors with the genetic mutation for colon cancer lived long enough, they would have developed the disease, just like us. Arbesfeld says her next step is to sequence samples from other sources for a larger follow-up study. She says understanding our genetic past can better explain the present. And understanding a disease’s genetic past can help to handle the disease’s future.

What does hypothesis mean?
a permanent change
special chemicals
the differences in living things
an idea or theory
What is the APC gene involved in?
digestion
photosynthesis
development of cancer
fertility
Understanding our genetic past can better explain the present.
genetic
historic
ancestors
society