The Reverend Billy Graham died Wednesday at his home in the American state of North Carolina, a spokesman said. Graham had long suffered from health problems, including cancer. He was 99 years old. Graham influenced American religious life for generations. He offered spiritual advice to many presidents and became the most widely heard Christian evangelist in history. Tall, with thick hair and clear blue eyes, Graham became a Southern Baptist clergyman in 1940. During his 70 years in public life, he spoke to more than 200 million people in 185 countries and territories. He and his supporters held massive gatherings called the Billy Graham Crusades. Thousands of people attended each rally, either in person or by satellite. They were held on every continent except Antarctica.