Britain’s parliament has rejected for a second time Prime Minister Theresa May’s Brexit deal to leave the European Union. British lawmakers voted 391 to 242 against May’s plan Tuesday, 17 days before Britain is to withdraw from the political and economic alliance. The vote meant Britain will have to choose: leaving the EU without a deal; delaying the March 29 departure date; or having a new Brexit vote. May told lawmakers before the vote, “If this vote is not passed tonight, if this deal is not passed, then Brexit could be lost.” On Wednesday, lawmakers will vote on whether Britain should leave the world’s biggest trading group without a deal. Business leaders warn that such an exit would cause severe disorder in markets and supply chains. Others say it could cause shortages of food and medicines. Supporters of Brexit argue the withdrawal would permit Britain to succeed and negotiate new trade deals across the world. However, parliament is expected to reject a “no-deal” Brexit as well.