The world’s biggest COVID-19 vaccine study started on Monday. A total of 30,000 planned volunteers will help test the effectiveness and safety of a shot developed by the National Institutes of Health and drug maker Moderna. The volunteers will each receive two doses of a shot. They will not know whether they are getting the real vaccine or a false version. Scientists will then closely follow the volunteers as they go about their daily activities. They want to see which group experiences a higher rate of infections, especially in areas where the virus still is spreading unchecked. There is still no guarantee that the experimental vaccine will offer protection. The study hopes to answer that question.