A new study involving an experimental drug showed improved survival in men with severe prostate cancer. Researchers say the drug may become a new way to treat patients with other hard-to-reach or inoperable cancers. The study tested a new kind of medicine called radiopharmaceuticals. These drugs deliver radiation directly to cancer cells. The drug in this case is a molecule that contains two parts: one that hunts for the cancer cells and another that kills them. Trillions of these molecules hunt down cancer cells, then they are killed by radiation. “You can treat tumors that you cannot see. Anywhere the drug can go, the drug can reach tumor cells,” said Dr. Frank Lin. He works at the National Cancer Institute helping to develop such medicine but did not take part in the study. The American Society of Clinical Oncology recently released the results of the study. The drug’s maker, Novartis, paid for the research. The company plans to seek approvals in the United States and Europe later this year. When cancer is found only in the prostate, radiation can be directed onto or inside the body. But those methods do not work well in more severe cases of prostate cancer. Each year, about 43,000 men in the United States are diagnosed with prostate cancer that has spread and no longer responds to usual treatment. The study involved 831 men with severe prostate cancer. Two-thirds were given the radiation drug, while the rest of the group were not. Patients received the drug every six weeks, up to six times. After about two years, those who received the drug did better, on average. The cancer was controlled for nearly nine months compared to about three months for the others. Survival was better, too about 15 months compared to 11 months.
Title: Radiation Drugs Hunt and Kill Cancer Cells
Content: <div id='article-page'><div id='article-content' data-media-url='//news-app-staging.s3.amazonaws.com' data-base-url='//news-app-staging.herokuapp.com' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/A.wav' data-capture-url='//staging.analytics.lingraphica.com/events/capture_news' data-article-title='Radiation Drugs Hunt and Kill Cancer Cells' data-article-id='5684'><script src='//news-app-staging.herokuapp.com/javascripts/getscripts.js'></script><link rel='stylesheet' href='//news-app-staging.herokuapp.com/stylesheets/article.css' type='text/css' /><div class='article'><p><span data-start-time='0' data-end-time='9667'>A new study involving an experimental drug showed improved survival in men with severe prostate cancer.</span> <span data-start-time='9667' data-end-time='20000'>Researchers say the drug may become a new way to treat patients with other hard-to-reach or inoperable cancers.</span> <span data-start-time='20000' data-end-time='26813'>The study tested a new kind of medicine called radiopharmaceuticals. </span> <span data-start-time='26813' data-end-time='32750'>These drugs deliver radiation directly to cancer cells. </span> <span data-start-time='32750' data-end-time='44063'>The drug in this case is a molecule that contains two parts: one that hunts for the cancer cells and another that kills them.</span> <span data-start-time='44063' data-end-time='52208'>Trillions of these molecules hunt down cancer cells, then they are killed by radiation.</span> <span data-start-time='52208' data-end-time='56604'>“You can treat tumors that you cannot see. </span> <span data-start-time='56604' data-end-time='64292'>Anywhere the drug can go, the drug can reach tumor cells,” said Dr. Frank Lin. </span> <span data-start-time='64292' data-end-time='73542'>He works at the National Cancer Institute helping to develop such medicine but did not take part in the study.</span> <span data-start-time='73542' data-end-time='81333'>The American Society of Clinical Oncology recently released the results of the study. </span> <span data-start-time='81333' data-end-time='86396'>The drug’s maker, Novartis, paid for the research. </span> <span data-start-time='86396' data-end-time='93979'>The company plans to seek approvals in the United States and Europe later this year.</span> <span data-start-time='93979' data-end-time='102563'>When cancer is found only in the prostate, radiation can be directed onto or inside the body.</span> <span data-start-time='102563' data-end-time='109583'>But those methods do not work well in more severe cases of prostate cancer. </span> <span data-start-time='109583' data-end-time='122667'>Each year, about 43,000 men in the United States are diagnosed with prostate cancer that has spread and no longer responds to usual treatment.</span> <span data-start-time='122667' data-end-time='129604'>The study involved 831 men with severe prostate cancer.</span> <span data-start-time='129604' data-end-time='136083'>Two-thirds were given the radiation drug, while the rest of the group were not. </span> <span data-start-time='136083' data-end-time='143021'>Patients received the drug every six weeks, up to six times.</span> <span data-start-time='143021' data-end-time='149938'>After about two years, those who received the drug did better, on average. </span> <span data-start-time='149938' data-end-time='157750'>The cancer was controlled for nearly nine months compared to about three months for the others. </span> <span data-start-time='157750' data-end-time='165333'>Survival was better, too about 15 months compared to 11 months.</span> </p></div><div class='control-buttons-sticky' style='display:none;'><div class='control-buttons'><button title='Back' class='back' disabled='disabled'></button><button title='Play' class='play' disabled='disabled'></button><button title='Pause' class='pause' style='display:none;'></button><button title='Forward' class='forward' disabled='disabled'></button><button class='finished-reading' style='display:none;'>Done</button></div></div></div><div id='article-media'><div id='media-image'><img src='https://news-app-production.s3.amazonaws.com/articles/5147/A.jpeg'/></div></div><div id='question-content' style='display:none;'><div class='vocabulary_question question-container' data-question-id=17554 data-hint-location='0' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/what_does_experimental_mean.wav'>What does experimental mean?</div><div class='choices' data-correct-choice='based on untested ideas or techniques and not yet established or finalized'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/excessive_or_extravagant.wav'><span>excessive or extravagant</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/based_on_untested_ideas_or_techniques_and_not_yet_established_or_finalized.wav'><span>based on untested ideas or techniques and not yet established or finalized</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/mysterious.wav'><span>mysterious</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/performed_or_occurring_as_a_result_of_a_sudden_inner_impulse.wav'><span>performed or occurring as a result of a sudden inner impulse</span></div></div></div><div class='multiple_choice_question question-container' data-question-id=17555 data-hint-location='0' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/which_type_of_cancer_did_the_study_involve.wav'>Which type of cancer did the study involve?</div><div class='choices' data-correct-choice='prostate cancer'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/lymphoma.wav'><span>lymphoma</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/prostate_cancer.wav'><span>prostate cancer</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/breast_cancer.wav'><span>breast cancer</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/melanoma.wav'><span>melanoma</span></div></div></div><div class='sentence_completion_question question-container' data-question-id=17556 data-hint-location='136083' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/_blank__received_the_drug_every_six_weeks_up_to_six_times.wav'><span class='blank'>Patients</span> received the drug every six weeks, up to six times.</div><div class='choices' data-correct-choice='Patients'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/doctors.wav'><span>Doctors</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/family_members.wav'><span>Family members</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/patients.wav'><span>Patients</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5147/lab_mice.wav'><span>Lab mice</span></div></div></div><div class='question-buttons'><button class='skip-button'></button><button class='hint-button'></button><button class='speak-button'></button></div></div></div>
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