Researchers used a brain cancer patient’s cells to make a model of a tumor to test treatments before using them on the body. The tumor model was created with 3D printing materials. The scientists removed a piece of the tumor from a patient with glioblastoma and used it to print a model of the tumor. That explanation comes from Professor Ronit Satchi-Fainaro, who led the research at Tel Aviv University in Israel. Glioblastoma is an aggressive form of brain cancer. The patient's blood is pumped through the printed tumor and then a drug or therapeutic treatment is pumped in. Earlier studies have used similar bioprinting methods to reproduce cancer environments. But the Tel Aviv University researchers say they are the first to print a viable tumor. Satchi-Fainaro said they have about two weeks to test the different therapies on a tumor and find a fitting treatment for the patient. A treatment is considered promising if the printed tumor shrinks or if it lowers metabolic activity. The research was released on Wednesday in the publication Science Advances. Glioblastoma is the most common form of brain cancer in adults. It spreads quickly to other parts of the brain, making it difficult to treat. Survival is around 40 percent in the first year and 17 percent in the second. That information is from the American Association of Neurological Surgeons. Researchers have often printed 3D tumor models to plan for surgery. But more recent developments have used live cells as a kind of printing substance to build up the parts of a tumor. Ofra Benny leads similar research at the Hebrew University of Jerusalem. She said using a patient's own cells to make 3D tumor models could be a game changer in the field of personalized medicine. The more these 3D models are made, the better the prediction for how a treatment will work on the patient’s tumor, she said.
Title: Cancer Patients’ Own Cells Used to Test Treatments
Content: <div id='article-page'><div id='article-content' data-media-url='//news-app-staging.s3.amazonaws.com' data-base-url='//news-app-staging.herokuapp.com' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/B.wav' data-capture-url='//staging.analytics.lingraphica.com/events/capture_news' data-article-title='Cancer Patients Own Cells Used to Test Treatments' data-article-id='5857'><script src='//news-app-staging.herokuapp.com/javascripts/getscripts.js'></script><link rel='stylesheet' href='//news-app-staging.herokuapp.com/stylesheets/article.css' type='text/css' /><div class='article'><p><span data-start-time='0' data-end-time='12833'>Researchers used a brain cancer patient’s cells to make a model of a tumor to test treatments before using them on the body. </span> <span data-start-time='12833' data-end-time='19479'>The tumor model was created with 3D printing materials.</span> <span data-start-time='19479' data-end-time='31271'>The scientists removed a piece of the tumor from a patient with glioblastoma and used it to print a model of the tumor. </span> <span data-start-time='31271' data-end-time='43979'>That explanation comes from Professor Ronit Satchi-Fainaro, who led the research at Tel Aviv University in Israel.</span> <span data-start-time='43979' data-end-time='49375'>Glioblastoma is an aggressive form of brain cancer.</span> <span data-start-time='49375' data-end-time='59833'>The patient's blood is pumped through the printed tumor and then a drug or therapeutic treatment is pumped in.</span> <span data-start-time='59833' data-end-time='69354'>Earlier studies have used similar bioprinting methods to reproduce cancer environments. </span> <span data-start-time='69354' data-end-time='77958'>But the Tel Aviv University researchers say they are the first to print a viable tumor.</span> <span data-start-time='77958' data-end-time='90167'>Satchi-Fainaro said they have about two weeks to test the different therapies on a tumor and find a fitting treatment for the patient.</span> <span data-start-time='90167' data-end-time='99938'>A treatment is considered promising if the printed tumor shrinks or if it lowers metabolic activity.</span> <span data-start-time='99938' data-end-time='108146'>The research was released on Wednesday in the publication Science Advances.</span> <span data-start-time='108146' data-end-time='115292'>Glioblastoma is the most common form of brain cancer in adults. </span> <span data-start-time='115292' data-end-time='122563'>It spreads quickly to other parts of the brain, making it difficult to treat. </span> <span data-start-time='122563' data-end-time='131333'>Survival is around 40 percent in the first year and 17 percent in the second. </span> <span data-start-time='131333' data-end-time='140000'>That information is from the American Association of Neurological Surgeons.</span> <span data-start-time='140000' data-end-time='147771'>Researchers have often printed 3D tumor models to plan for surgery. </span> <span data-start-time='147771' data-end-time='158417'>But more recent developments have used live cells as a kind of printing substance to build up the parts of a tumor.</span> <span data-start-time='158417' data-end-time='166875'>Ofra Benny leads similar research at the Hebrew University of Jerusalem. </span> <span data-start-time='166875' data-end-time='178646'>She said using a patient's own cells to make 3D tumor models could be a game changer in the field of personalized medicine.</span> <span data-start-time='178646' data-end-time='189625'>The more these 3D models are made, the better the prediction for how a treatment will work on the patient’s tumor, she said.</span> </p></div><div class='control-buttons-sticky' style='display:none;'><div class='control-buttons'><button title='Back' class='back' disabled='disabled'></button><button title='Play' class='play' disabled='disabled'></button><button title='Pause' class='pause' style='display:none;'></button><button 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with a closed end, worn to protect the finger and push the needle in sewing</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/a_flashing_light_on_a_vehicle_to_show_that_it_is_about_to_change_lanes_or_turn.wav'><span>a flashing light on a vehicle to show that it is about to change lanes or turn</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/a_swelling_of_a_part_of_the_body_generally_without_inflammation_caused_by_an_abnormal_growth_of_tissue_whether_benign_or_malignant.wav'><span>a swelling of a part of the body, generally without inflammation, caused by an abnormal growth of tissue, whether benign or malignant</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/a_person_who_tunes_musical_instruments_especially_pianos.wav'><span>a person who tunes musical instruments, especially pianos</span></div></div></div><div class='multiple_choice_question question-container' data-question-id=18007 data-hint-location='31271' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/in_which_country_did_this_bioprinting_take_place.wav'>In which country did this bioprinting take place?</div><div class='choices' data-correct-choice='Israel'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/israel.wav'><span>Israel</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/norway.wav'><span>Norway</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/peru.wav'><span>Peru</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/the_united_states.wav'><span>The United States</span></div></div></div><div class='sentence_completion_question question-container' data-question-id=18008 data-hint-location='140000' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/researchers_have_often_printed_3d_tumor_models_to_plan_for__blank__.wav'>Researchers have often printed 3D tumor models to plan for <span class='blank'>surgery</span>. </div><div class='choices' data-correct-choice='surgery'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/surgery.wav'><span>surgery</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/january.wav'><span>January</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/parade.wav'><span>parade</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5303/basement.wav'><span>basement</span></div></div></div><div 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