Drug companies Pfizer and BioNTech said Monday that three low-dose injections of their COVID-19 vaccine have shown to be effective in protecting children under age five. The companies made the announcement after carrying out new experiments, or trials, involving the youngest population group. They plan to provide information about the trials to the U.S. Food and Drug Administration, FDA, as soon as this week. The estimated 18 million children under five are the only Americans who have not yet been approved to receive a COVID-19 vaccine. Pfizer and BioNTech have said the amount of vaccine used in their shots for children under five is much less about one-tenth lower than the amount used in injections for adults. In earlier trials, researchers for the companies said two shots did not seem quite strong enough to effectively protect young children. So they decided to give a third shot to more than 1,600 individuals aged six months to four years. The new trial was carried out during last winter’s spread of the Omicron version of COVID-19. In a statement released Monday, Pfizer and BioNTech said the extra shot increased levels of virus-fighting antibodies in the youngest age group. The companies said the levels meet FDA requirements for emergency approval of the vaccine. Pfizer and BioNTech said early data suggests the three-shot series is more than 80 percent effective in preventing symptomatic COVID-19
Title: Pfizer: 3 Shots Effective Against COVID-19 in Children under 5
Content: <div id='article-page'><div id='article-content' data-media-url='//news-app-staging.s3.amazonaws.com' data-base-url='//news-app-staging.herokuapp.com' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/C31.wav' data-capture-url='//staging.analytics.lingraphica.com/events/capture_news' data-article-title='Pfizer: 3 Shots Effective Against COVID-19 in Children under 5' data-article-id='6144'><script src='//news-app-staging.herokuapp.com/javascripts/getscripts.js'></script><link rel='stylesheet' href='//news-app-staging.herokuapp.com/stylesheets/article.css' type='text/css' /><div class='article'><p><span data-start-time='0' data-end-time='19146'>Drug companies Pfizer and BioNTech said Monday that three low-dose injections of their COVID-19 vaccine have shown to be effective in protecting children under age five.</span> <span data-start-time='19146' data-end-time='30688'>The companies made the announcement after carrying out new experiments, or trials, involving the youngest population group.</span> <span data-start-time='30688' data-end-time='42604'>They plan to provide information about the trials to the U.S. Food and Drug Administration, FDA, as soon as this week.</span> <span data-start-time='42604' data-end-time='56063'>The estimated 18 million children under five are the only Americans who have not yet been approved to receive a COVID-19 vaccine.</span> <span data-start-time='56063' data-end-time='74250'>Pfizer and BioNTech have said the amount of vaccine used in their shots for children under five is much less about one-tenth lower than the amount used in injections for adults.</span> <span data-start-time='74250' data-end-time='86625'>In earlier trials, researchers for the companies said two shots did not seem quite strong enough to effectively protect young children.</span> <span data-start-time='86625' data-end-time='97979'>So they decided to give a third shot to more than 1,600 individuals aged six months to four years.</span> <span data-start-time='97979' data-end-time='107458'>The new trial was carried out during last winter’s spread of the Omicron version of COVID-19.</span> <span data-start-time='107458' data-end-time='121583'>In a statement released Monday, Pfizer and BioNTech said the extra shot increased levels of virus-fighting antibodies in the youngest age group.</span> <span data-start-time='121583' data-end-time='130833'>The companies said the levels meet FDA requirements for emergency approval of the vaccine.</span> <span data-start-time='130833' data-end-time='145396'>Pfizer and BioNTech said early data suggests the three-shot series is more than 80 percent effective in preventing symptomatic COVID-19</span> </p></div><div class='control-buttons-sticky' style='display:none;'><div class='control-buttons'><button title='Back' class='back' disabled='disabled'></button><button title='Play' class='play' disabled='disabled'></button><button title='Pause' class='pause' style='display:none;'></button><button title='Forward' class='forward' disabled='disabled'></button><button class='finished-reading' style='display:none;'>Done</button></div></div></div><div id='article-media'><div id='media-image'><img src='https://news-app-production.s3.amazonaws.com/articles/5545/C31.jpg'/></div></div><div id='question-content' style='display:none;'><div class='vocabulary_question question-container' data-question-id=18668 data-hint-location='130833' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/which_is_a_definition_of_the_word_symptomatic.wav'>Which is a definition of the word symptomatic?</div><div class='choices' data-correct-choice='a change in the body or mind which indicates that a disease is present'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/a_change_in_the_body_or_mind_which_indicates_that_a_disease_is_present.wav'><span>a change in the body or mind which indicates that a disease is present</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/done_or_acting_according_to_a_fixed_plan_or_system_methodical.wav'><span>done or acting according to a fixed plan or system; methodical</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/working_by_itself_with_little_or_no_direct_human_control.wav'><span>working by itself with little or no direct human control</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/treating_complex_issues_and_problems_as_if_they_were_much_simpler_than_they_really_are.wav'><span>treating complex issues and problems as if they were much simpler than they really are</span></div></div></div><div class='multiple_choice_question question-container' data-question-id=18669 data-hint-location='0' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/how_many_doses_of_the_vaccine_have_shown_to_be_effective_in_children_under_5.wav'>How many doses of the vaccine have shown to be effective in children under 5?</div><div class='choices' data-correct-choice='3'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/4.wav'><span>4</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/2.wav'><span>2</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/3.wav'><span>3</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/1.wav'><span>1</span></div></div></div><div class='sentence_completion_question question-container' data-question-id=18670 data-hint-location='42604' style='display:none;'><div class='question' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/the_estimated_18__blank__children_under_five_are_the_only_americans_who_have_not_yet_been_approved_to_receive_a_covid19_vaccine.wav'>The estimated 18 <span class='blank'>million</span> children under five are the only Americans who have not yet been approved to receive a COVID-19 vaccine.</div><div class='choices' data-correct-choice='million'><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/million.wav'><span>million</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/billion.wav'><span>billion</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/thousand.wav'><span>thousand</span></div><div class='choice' data-sound-name='https://news-app-production.s3.amazonaws.com/articles/5545/hundred.wav'><span>hundred</span></div></div></div><div class='question-buttons'><button class='skip-button'></button><button class='hint-button'></button><button class='speak-button'></button></div></div></div>
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